University of Heidelberg

SFB 488

Contact

Coordinator:

Prof. Dr. Joachim Wittbrodt
Phone: +49-6221-54-6499
Fax:     +49-6221-54-5639
Jochen.wittbrodt(at)zoo.uni-heidelberg.de

Administration:

Ute Volbehr
Phone: +49-6221-54-6498
Fax:     +49-6221-54-5639
sfb488(at)uni-hd.de

Postal address:

University of Heidelberg
Heidelberg Institute of Zoology
Im Neuenheimer Feld 230
69120 Heidelberg
Germany


Home > Projects

Projects

Jump to: Project Area A | Project Area B | Project Area D | Junior Group | Project Area Z

Project Area A

Neural induction, pattern formation and cell fate determination

No Title Area of expertise
Project leader, institution
A1 Functional characterization of a novel Wnt regulator Molecular and Cell Biology, Developmental Biology
C. Niehrs / C.-M. Sirrenberg-Cruciat
German Cancer Research Center (DKFZ), Heidelberg
A5 Mechanisms of specification and delamination of Neural Crest progenitors
Cell Biology; Developmental Neurobiology; Cell specification, Snail, FoxD3, Sox9, MITF, regulation of cell migration vis-à-vis cell specification, epithelial-mesenchymal conversion, cell adhesion, cytoskeletal assembly, cell cycle regulation C. Kalcheim
Hebrew University, Israel
A6 Specification and maintenance of chromaffin cells and their preganglionic innervation

Neuroanatomy, Developmental Neurobiology

K. Unsicker /
C. Kalcheim

Neuroanatomy, IZN of the University of Heidelberg / Hebrew University, Jerusalem, Israel
A8 Retinal growth and regeneration Molecular and Cell Biology, Neurobiology
J. Wittbrodt
Heidelberg Institute of Zoology, University of Heidelberg
A12 Patterning of an ancient nervous system. Analysis of regulatory genes in the cnidarian nervous system Developmental Biology, Neurobiology
T. Holstein
Heidelberg Institute of Zoology, University of Heidelberg
A14 Specification of peripheral neurons at the lateral neuroectoderm border in the marine annelid Platynereis dumerilii Neural Crest, sensory placodes, annelids, neurodevelopment, molecular profiling, peripheral system, cell type evolution D. Arendt
Heidelberg Institute of Zoology, University of Heidelberg
A15 Mechanical regulation of neuronal differentiation in vivo Developmental and Cell Biology
D. Gilmour
European Molecular Biology Laboratory (EMBL)
A17 Identification of cis-regulatory grammar controlling neuronal development in vertebrate Bioinformatics, Developmental Biology
L. Ettwiller
Heidelberg Institute of Zoology, University of Heidelberg
A18 Establishment of neuroanatomical asymmetries in the zebrafish brain Developmental Biology, Developmental Neurobiology M. Carl
Medical Faculty Mannheim,
University of Heidelberg

Jump to: Project Area A | Project Area B | Project Area D | Junior Group | Project Area Z

Project Area B

Axonal growth and pathfinding

No Title Area of expertise
Project leader, institution
B4 The Role of the cell adhesion molecule DM-GRASP and its effectors in axon growth and navigation in vivo
Developmental Biology G.E. Pollerberg
Heidelberg Institute of Zoology, University of Heidelberg
B6 Functional roles of Semaphorin-Plexin-B interactions in mechanisms governing neuronal specification and connectivity
Molecular pharmacology; mechanisms of neuronal morphogenesis; migration and pattern formation
R. Kuner
Institute of Pharmacology, University of Heidelberg

B8 Functional role of the RhoGAP gene MEGAP in neuronal development Developmental Neurobiology, Cell Biology, Human and Mouse Genetics G. Rappold
Department of Human Genetics, University of Heidelberg
B9 Control of mouse brain development by primary cilia Developmental neurobiology, Axonal growth and pathfinding K. Tucker
Interdisciplinary Center for Neurosciences (IZN)
University of Heidelberg

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Project Area D

Molecular bases of synapse and network formation

No Title Area of expertise
Project leader, institution
D6 The role of the nuclear receptor ´tailless´ in development and adult neural stem cells
Neurobiology; Molecular Biology
G. Schütz
German Cancer Research Center, DKFZ, Heidelberg
D7 Analysis of GADD45-mediated epigenetic control of activity-dependent neuronal survival
Molecular and Cellular Neurobiology
H. Bading
Institute of Neurobiology, University of Heidelberg
D12 The role of GABA-A receptors in GnRH neurons and of olfactory bulb GnRH neurons of reproduction Molecular Biology
P. Seeburg
Max-Planck-Institute for Medical Research, Heidelberg
D13 Functional maturation of patterned network activity in the dentate gyrus Neurophysiology, Developmental Neuroscience A. Draguhn
Institute of Physiology and Pathophysiology
University of Heidelberg
D16 Role of presynaptic NMDA-receptors during the development of neuromuscular junctions in Drosophila Developmental Neurobiology, Synaptic Plasticity C. Schuster
Institute of Neurobiology, University of Heidelberg
D17 Signaling pathways in tangentially migrating neuroblasts Molecular and Cellular Neurobiology, Neurogenesis in the adult brain
H. Monyer
Department of Clinical Neurobiology, University of Heidelberg
D18 Control of synapse assembly and development of neuromuscular junctions in genetically engineered mouse models Developmental Neurobiology; Neurogenetics U. Müller / V.Witzemann
Institute for Pharmacy and Molecular Biotechnology, University of Heidelberg /
Department of Cellphysiology, Max-Planck-Institute for Medical Research Heidelberg
D20 Regulation of SVZ precursors proliferation by EGFR signalling Neurogenesis, neural stem cells, SVZ, proliferation, growth factor F. Ciccolini
Institute of Neurobiology, University of Heidelberg

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Junior Group N1

No Title Area of expertise
Project leader, institution
N1 Investigating the role of neuronal microRNAs in local translation of dendritic mRNAs in mammalian cells
Molecular and Cellular Neurobiology, Synapse development
G. Schratt
SFB 488 Junior Group, IZN, University of Heidelberg

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Project group Z

Central Services

No Title Area of expertise
Project leader, institution
Z1 Administrative project
n.a.
U. Volbehr / J. Wittbrodt
Heidelberg Institute of Zoology, University of Heidelberg
Z3 Confocal Live Cell Microscopy
n.a. U. Engel / T. Holstein / J. Wittbrodt
Nikon Imaging Center / Heidelberg Institute of Zoology, University of Heidelberg

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